Catechol-o-methyltransferase inhibitors : Clinical potential in the treatment of Parkinson's diseaseDINGEMANSE, J.Drug development research. 1997, Vol 42, Num 1, pp 1-25, issn 0272-4391Article

Pharmacokinetic/Pharmacodynamic Modeling of Renin Biomarkers in Subjects Treated With the Renin Inhibitor AliskirenHONG, Y; DINGEMANSE, J; MAGER, D. E et al.Clinical pharmacology and therapeutics. 2008, Vol 84, Num 1, pp 136-143, issn 0009-9236, 8 p.Article

Evolving bioanalytical methods for the cardiovascular drug bosentanDELL, D; LAUSECKER, B; HOPFGARTNER, G et al.Chromatographia (Wiesbaden). 2002, Vol 55, pp S.115-S.120, issn 0009-5893, SUPConference Paper

Tyramine pharmacodynamics during combined administration of lazabemide and moclobemideDINGEMANSE, J; HUSSAIN, Y; KORN, A et al.International journal of clinical pharmacology and therapeutics. 1996, Vol 34, Num 4, pp 172-177, issn 0946-1965Article

Pharmacokinetic modeling of the anticonvulsant response of oxazepam in rats using the pentylenetetrazol threshold concentration as pharmacodynamic measureDINGEMANSE, J; SOLLIE, F. A. E; BREIMER, D. D et al.Journal of pharmacokinetics and biopharmaceutics. 1988, Vol 16, Num 2, pp 203-228, issn 0090-466XArticle

Application of serial sampling of cerebrospinal fluid in pharmacodynamic studies with a drug active in the CNS: heptabarbital concentrations at onset and offset of loss of righting reflex in ratsDINGEMANSE, J; HUTSON, P. H; LANGEMEIJER, M. W. E et al.Neuropharmacology. 1988, Vol 27, Num 5, pp 467-474, issn 0028-3908Article

Effect of severe renal impairment on the pharmacokinetics and tolerability of the parenteral endothelin antagonist tezosentanVAN GIERSBERGEN, P. L. M; DINGEMANSE, J.International journal of clinical pharmacology and therapeutics. 2003, Vol 41, Num 6, pp 261-266, issn 0946-1965, 6 p.Article

Determination of the threshold for convulsions by direct cortical stimulationVOSKUYL, R. A; DINGEMANSE, J; DANHOF, M et al.Epilepsy research. 1989, Vol 3, Num 2, pp 120-129, issn 0920-1211Article

Pharmacokinetic-pharmacodynamic modeling of CNS drug effects: an overviewDINGEMANSE, J; DANHOF, M; BREIMER, D. D et al.Pharmacology & therapeutics (Oxford). 1988, Vol 38, Num 1, pp 1-52, issn 0163-7258Article

PHARMACOKINETICS AND BIOAVAILABILITY OF INTRAVENOUS, ORAL, AND RECTAL NITRAZEPAM IN HUMANSJOCHEMSEN R; HOGEN DOORN JJH; DINGEMANSE J et al.1982; JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS; ISSN 0090-466X; USA; DA. 1982; VOL. 10; NO 3; PP. 231-248; BIBL. 15 REF.Article

Tyramine pressor sensitivity in healthy subjects during combined treatment with moclobemide and selegilineKORN, A; WAGNER, B; MORITZ, E et al.European journal of clinical pharmacology. 1996, Vol 49, Num 4, pp 273-278, issn 0031-6970Article

Influence of severe renal dysfunction on the pharmacokinetics and metabolism of bosentan, a dual endothelin receptor antagonistDINGEMANSE, J; VAN GIERSBERGEN, P. L. M.International journal of clinical pharmacology and therapeutics. 2002, Vol 40, Num 7, pp 310-316, issn 0946-1965Article

Pharmacokinetics and pharmacodynamics of single and multiple doses of the MAO-B inhibitor lazabemide in healthy subjectsDINGEMANSE, J; WOOD, N; JORGA, K et al.British journal of clinical pharmacology. 1997, Vol 43, Num 1, pp 41-47, issn 0306-5251Article

Potent COMT inhibition by Ro 40-7592 in the periphery and in the brain : preclinical and clinical findingsZÜRCHER, G; DINGEMANSE, J; DA PRADA, M et al.Advances in neurology. 1993, Vol 60, pp 641-647, issn 0091-3952Article

Monoaminoxydase-Hemmstoffe und RIMA-Substanzen in der Anästhesie = Monoamine oxidase inhibitors and RIMA substances in anaesthesiaTOLKSDORF, W; BAIER, D; DINGEMANSE, J et al.Anästhesiologie und Intensivmedizin (Erlangen). 1992, Vol 33, Num 7, pp 175-185, issn 0170-5334Article

Altered pharmacokinetics-pharmacodynamic relationship of heptabarbital in experimental renal failure in ratsDINGEMANSE, J; POLHUIJS, M; DANHOF, M et al.The Journal of pharmacology and experimental therapeutics. 1988, Vol 246, Num 1, pp 371-376, issn 0022-3565Article

Pharmacodynamics of tolerance development to the anesthetic and anticonvulsant effects of phenobarbital in ratsDINGEMANSE, J; HAMETER, B. M; DANHOF, M et al.Journal of pharmaceutical sciences. 1990, Vol 79, Num 3, pp 207-211, issn 0022-3549Article

Pharmacokinetics, pharmacodynamics and the pharmacokinetic/ pharmacodynamic relationship of zolpidem in healthy subjectsDE HAAS, S. L; SCHOEMAKER, R. C; VAN GERVEN, J. M. A et al.Journal of psychopharmacology (Oxford). 2010, Vol 24, Num 11, pp 1619-1629, issn 0269-8811, 11 p.Article

Pharmacokinetics and pharmacodynamics of the acetylcholinesterase inhibitor metrifonate in patients with renal impairmentDINGEMANSE, J; HALABI, A; KLEINBLOESEM, C. H et al.Therapeutic drug monitoring. 1999, Vol 21, Num 3, pp 310-316, issn 0163-4356Article

Comparative single- and multiple-dose pharmacokinetics of levodopa and 3-O-methyldopa following a new dual-release and a conventional slow-release formulation of levodopa and benserazide in healthy subjectsGASSER, U. E; CREVOISIER, C; OUWERKERK, M et al.European journal of pharmaceutics and biopharmaceutics. 1998, Vol 46, Num 2, pp 223-228, issn 0939-6411Article

Integrated pharmacokinetics and pharmacodynamics of Ro 48-8684, a new benzodiazepine, in comparison with midazolam during first administration to healthy male subjectsVAN GERVEN, J. M. A; RONCARI, G; SCHOEMAKER, R. C et al.British journal of clinical pharmacology. 1997, Vol 44, Num 5, pp 487-493, issn 0306-5251Article

Diazepam reverses the effects of pentylenetetrtazole in rat pups by acting at type 2 benzodiazepine receptorsJOHNSTON, A. L; FILE, S. E; DINGEMANSE, J et al.Pharmacology, biochemistry and behavior. 1989, Vol 32, Num 3, pp 823-825, issn 0091-3057Article

Modification of the cardiovascular effects of ephedrine by the reversible monoamine oxidase A-inhibitor MoclobemideDINGEMANSE, J; GUENTERT, T; GIESCHKE, R et al.Journal of cardiovascular pharmacology. 1996, Vol 28, Num 6, pp 856-861, issn 0160-2446Article

Comparative pharmacodynamics of Ro 41-3696, a new hypnotic, and zolpidem after night-time administration to healthy subjectsDINGEMANSE, J; BURY, M; BOCK, J et al.Psychopharmacologia. 1995, Vol 122, Num 2, pp 169-174, issn 0033-3158Article

An update of recent moclobemide interaction dataDINGEMANSE, J.International clinical psychopharmacology. 1993, Vol 7, Num 3-4, pp 167-180, issn 0268-1315Conference Paper